Ageology physicians agree that there is convincingly strong evidence from extensive research over the last three decades on the beneficial effects of fish oil therapy for cardiovascular disease prevention, particularly in patients with high risk for sudden cardiac death. Current recommendations suggest that patients with known heart disease should consume 800–1000 mg/d of combined EPA/DHA, and individuals with no known disease should consume at least 500 mg/d. These doses of EPA/DHA can be obtained by consuming fatty fish or by taking fish oil supplements. Patients with high triglyceride levels will benefit from large doses (3–4 g/d) of EPA/DHA, a dose that almost certainly would require fish oil supplements.